Impaired triglyceride tolerance in hemodialysis patients with different apolipoprotein E (apo E) isoforms.
نویسندگان
چکیده
Uremic dyslipidemia is an important risk factor for accelerated atherosclerosis, contributing to the many times higher cardiovascular mortality of hemodialysis (HD) patients (pts) in comparison to nonuremic population1. The influence of genetic determinants in this disorder has been widely studied, including apo E genetic variation and its relationship to cardiac and cerebrovascular disease. Owing to different affinities of apo E isoforms for apo B/E and apo E receptors, apo E polymorphism has an impact on lipid metabolism and lipid plasma levels2, 3.
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ورودعنوان ژورنال:
- Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia
دوره 146 2 شماره
صفحات -
تاریخ انتشار 2002